IMMUNITY AND PROTECTIVE INOCULATION

Protective Inoculation against Cholera

of anti-cholera vaccine. It is divided into three parts, viz., the preparation of an anti-cholera vaccine, immunization of man against cholera and the anti-cholera vaccine after its devitalisation. It is pointed out that such is the variability of the germ of cholera that it is essential to first select the particular variety of the germ which is to be selected as " authenic and appropriate." W...

Intrahepatic genetic inoculation of hepatitis C virus RNA confers cross-protective immunity.

Naturally occurring hepatitis C virus (HCV) infection has long been thought to induce a weak immunity which is insufficient to protect an individual from subsequent infections and has cast doubt on the ability to develop effective vaccines. A series of intrahepatic genetic inoculations (IHGI) with type 1a HCV RNA were performed in a chimpanzee to determine whether a form of genetic immunization...

Protective Cellular Immunity Against Influenza Virus Induced by Plasmid Inoculation of Newborn Mice

Neonate organisms display an intrinsic disability to mount effective immune responses to infectious agents or conventional vaccines. Whereas low doses of antigens trigger a suboptimal response, higher doses are frequently associated with tolerance induction. We investigated the ability of a plasmid-expressing nucleoprotein of influenza virus to prime a specific cellular immune response when adm...

Mediate Protective Tuberculosis Immunity

Eosinophils Mediate Protective Immunity